The purpose of the ACCORD Eye Study is to investigate the effects of the ACCORD interventions (blood sugar control, blood pressure control, and blood lipids control) on eye disease (retinopathy) in ACCORD participants, all of whom have diabetes. Retinopathy associated with diabetes is the leading cause of acquired blindness in adults in the US. Participants in the ACCORD Eye Study will have fundus (part of the retina, or back of the eye) photographs taken within four months of randomization and again four years later.

The primary outcome variable of the ACCORD Eye Study is the combined outcome of progression of diabetic retinopathy of at least 3 stages on the ETDRS scale, photocoagulation (laser therapy for diabetic eye disease), or vitrectomy (a type of surgery for diabetic eye disease).

There will be 4065 participants recruited to the study at baseline and we will examine the effects of blood sugar control, lipid control, and blood pressure control on the primary outcome. If this study is positive, the studied treatments could be used more widely to help prevent diabetes-related blindness.

Download ACCORD-EYE Protocol >>
Download ACCORD-Eye Forms, Labeling, Study Conventions and Imaging Procedures >>
Fundus Photograph Reading Center Photographer Information >>
Modified 7-Standard Field Photography Tutorial >>
Photographer Training Conference Call, August 2007 >>
Download Follow-Up Forms (Completed by Ophthalmologist) >>

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